Researchers have identified Jo Cameron, a 71-year-old woman from Scotland, who has lived her entire life virtually free of pain, fear, or anxiety — and with an extraordinary ability to heal from injuries with minimal scarring.
Far from a superpower, this remarkable resilience is the result of a rare genetic mutation.
Jo carries two unusual genetic alterations: one in a gene known as FAAH, and another in a nearby stretch of so-called “junk” DNA, newly named FAAH-OUT.
Together, these changes make Jo almost completely insensitive to pain. She often fails to notice burns or cuts until she smells burning flesh or sees bleeding, yet her wounds close quickly and leave little to no scarring.
This rare genetic combination not only shields her from physical pain but also appears to keep her emotionally calm and free from anxiety.
Scientists hope that studying Jo’s unique biology could pave the way for new, safer therapies to treat pain, anxiety, and wounds — potentially offering relief to millions without the risks of addictive painkillers.
